Overview of services:

A full range of diagnostic services are available in the Department of Surgical and Molecular Pathology. State of the art technology ensures that the most sophisticated diagnostic modalities are available. Techniques include frozen sections and fixed tissue, light microscopy, immunohistochemistry.

Special areas of expertise include:
Breast Pathology
• Dermatopathology
• Gastrointestinal & Hepatic
• Genitourinary Pathology
• Gynecologic Pathology
• Head and Neck Pathology
• Pulmonary Pathology
• Renal Pathology
• Soft Tissue Pathology
• Thyroid

Consultant pathologists: Dr. Ilona Péter, Dr. Klára Éles, Dr. Nóra Jani, Dr. Judit Laczkó-Tamás, Dr. Zsuzsa Sándor, Dr. Tamás Strausz, Dr. János Szőke, Dr. Erika Tóth, Dr. Nóra Udvarhelyi, Dr. Ildikó Vereczkey, Dr. Eszter Vincze, Dr. Endre Zs. Tóth

Residents: Dr. László Báthory-Fülöp, Dr. Katalin Kóczián, Dr. András Lantos, Dr. Maja Leiner, Dr. Krisztina Oláh, Dr. Eszter Papp, Dr. Ferenc Pintér, Dr. András Slezák, Dr. Réka Tőkés, Dr. Orsolya Virágh-Kiss

Surgical Pathology:
Good medical practice requires a tissue diagnosis prior to planning and initiating therapy.
The field of surgical pathology evaluates tissues removed from living patients during surgery or other types of invasive procedures in order to:
• Diagnose a disease and aid in planning a treatment
• Provide information regarding prognosis such as:
◦ Status of surgical margins (complete or incomplete removal of disease)
◦ Size and extent of disease, including tumor invasion into adjacent structures
◦ Tumor grade (well, moderately, or poorly differentiated)
◦ Presence of metastasis to regional lymph nodes or distant organs

Molecular Pathology:
Molecular Pathology Laboratory, directed by Dr. Erika Toth, is a growing service area focused on the use of nucleic acid-based techniques such as in-situ hybridization, real-time PCR and next generation sequencing. Spanning both the anatomic and clinical disciplines, state-of-the-art molecular pathology tests increase the specificity of disease diagnoses for identification and classification, they clarify the prognosis and predictions for the potential behavior of disease, and they determine the best therapeutic approaches and responses. Molecular pathology is becoming increasingly significant for the prediction of response to chemotherapy and radiation, the detection of residual disease.
With real-time PCR for mutational analysis and next generation sequencing, our current molecular pathology service volume is at over three thousand cases per year already.
Tests currently offered include microsatellite instability, RAS mutational analysis (sequencing) for colorectal and other cancers, EGFR mutational analysis (sequencing) for multiple cancers, BRAF mutational analysis for melanoma.
Turnaround Time is less than 10 days.
Pathologists working in Molecular Lab: Dr. Tamás Strausz, Dr. Klára Éles
Chief biologist: Dr. Erzsébet Csernák

Department of Surgical and Molecular Pathology contact:
Secretariat:
- Zsuzsanna Werly, Phone: 061-224-8600/3709, 1371; Fax: 061-224-8671; e-mail: werlyzs@oncol.hu
- Erika Szőke, Phone: 061-224-8600/2384, 3219; e-mail: szoke.erika@oncol.hu

Molecular Lab contact:
- Viktória Sipos, Lászlóné Szilágyi, Phone: 061-224-8600/2557; Fax: 061-224-8675; e-mail: sipos.viktoria@oncol.hu, szilagyi.laszlone@oncol.hu