2) Research tasks

Our Department is actively participating in various research programs which aimed to detect and identify genetic risk alleles for development of hereditary cancers.

The head of Department also lead the Hungarian Academy financed MTA-SE Lendület Hereditary Endocrine Tumours Research group. This group is multidisciplinary: molecular biologist, MDs, clinical geneticist, bioinformaticians, chemist are working together (www.endobioinfo.hu). Of endocrine tumors the hereditary medullary thyroid cancer, hereditary pheochromocytoma/paraganglioma syndromes, gastro-entero-pancreatic neuroendocrine tumors, adrenal and pituitary tumors are in the main focus. The group performs genetic, epigenetic, cell biology and biochemical studies in order to identify the molecular background of these tumours and to reveal potential novel therapeutical targets.
Resistance against hormonal treatment is also in our main focus. Particularly we perform research in deciphering the mechanism behind glucocorticoid receptor mediated resistance.